Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14143439 | 0.93 | F10 (0.65) | F10KLKB1KCNH2 | |
| SCHEMBL4705150 | 0.93 | F10 (0.65) | F10KLKB1KCNH2 | |
| SCHEMBL8466873 | 0.88 | F10 (0.57) | F10KLKB1KCNH2 | |
| SCHEMBL14039720 | 0.88 | F10 (0.73) | F10KLKB1 | |
| SCHEMBL3828697 | 0.86 | F10 (0.64) | F10KLKB1KCNH2 | |
| SCHEMBL3832127 | 0.86 | F10 (0.58) | F10KLKB1KCNH2 | |
| SCHEMBL3834297 | 0.85 | F10 (0.65) | F10KLKB1KCNH2 | |
| SCHEMBL8445059 | 0.85 | F10 (0.49) | F10KLKB1KCNH2 | |
| SCHEMBL3835341 | 0.85 | F10 (0.65) | F10KLKB1KCNH2 | |
| SCHEMBL3832111 | 0.84 | F10 (0.82) | F10KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287674-A1 | Inhibitors of Factor XA and Other Serine Proteases Involved in the Coagulation Cascade | WARNER-LAMBERT COMPANY LLC | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287674-A1 | Inhibitors of Factor XA and Other Serine Proteases Involved in the Coagulation Cascade | TFPI, F11, F2 | F10 11/4885KLKB1 116/4885KCNH2 3858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.