Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | P4HB | P07237 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10355976 | 0.82 | MAPT (0.54) | MAPTMAPK1KDM4ENSD2P4HB | |
| SCHEMBL9642618 | 0.81 | MAPT (0.53) | MAPTMAPK1KDM4ENSD2P4HB | |
| SCHEMBL4485448 | 0.81 | MAPT (0.64) | MAPTMAPK1KDM4ENSD2P4HB | |
| SCHEMBL6365480 | 0.78 | MAPK1 (0.64) | MAPTMAPK1KDM4ENSD2DHFR | |
| SCHEMBL11580274 | 0.78 | MAPT (0.55) | MAPTMAPK1KDM4ENSD2P4HB | |
| SCHEMBL5187613 | 0.77 | MAPT (0.68) | MAPTMAPK1KDM4ENSD2P4HB | |
| SCHEMBL14207786 | 0.77 | MAPT (0.73) | MAPTMAPK1KDM4ENSD2P4HB | |
| SCHEMBL26804289 | 0.76 | MAPK1 (0.43) | MAPTMAPK1KDM4ENSD2CDC25A | |
| SCHEMBL4469259 | 0.76 | MAPK1 (0.56) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL4465042 | 0.76 | MAPT (0.89) | MAPTMAPK1KDM4ENSD2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236786-B1 | Guest-host liquid crystal composition and guest-host liquid crystal display device | TOSHIBA KK (JP) | 2008-10-08 | — | — | EP | disclosed |