⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14287480 | 0.75 | LMNA (0.42) | — | |
| SCHEMBL13559397 | 0.66 | LMNA (0.37) | — | |
| SCHEMBL23874498 | 0.60 | LMNA (0.33) | — | |
| SCHEMBL12918364 | 0.59 | GRIN1 (0.63) | — | |
| SCHEMBL30235030 | 0.58 | LMNA (0.50) | — | |
| SCHEMBL13573456 | 0.58 | LMNA (0.46) | — | |
| SCHEMBL466044 | 0.58 | LMNA (0.32) | — | |
| SCHEMBL7323509 | 0.58 | LMNA (0.32) | — | |
| SCHEMBL597801 | 0.57 | ALDH1A1 (0.39) | — | |
| SCHEMBL3783240 | 0.57 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130550-A1 | DIAMONDOID DERIVATIVES POSSESSING THERAPEUTIC ACTIVITY IN THE TREATMENT OF NEUROLOGIC DISORDERS | CHEVRON U.S.A, INC. (US) | 2008-10-30 | — | — | WO | disclosed |
| EP-1982970-A1 | Diamondoid derivatives possessing therapeutic activity in the treatment of neurologic disorders | Chevron USA, Inc. (US) | 2008-10-22 | — | — | EP | disclosed |