Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.51 |
| ▸ | SRC | P12931 | 8/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5619944 | 0.75 | SRC (0.56) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL10322497 | 0.74 | POLB (0.50) | KDM4ETSHRPIK3CANRP1MTOR | |
| SCHEMBL5659394 | 0.72 | FGFR1 (0.45) | FGFR1SRCPDGFRBPDGFRAPKMYT1 | |
| SCHEMBL29536840 | 0.72 | FGFR1 (0.45) | FGFR1SRCPDGFRBPDGFRAPKMYT1 | |
| SCHEMBL14161489 | 0.71 | RIPK2 (0.46) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL10323700 | 0.71 | ALDH1A1 (0.43) | TSHRPIK3CAPIK3CBMTOR | |
| SCHEMBL16986331 | 0.70 | FGFR1 (0.61) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| Ethane SCHEMBL5761899 | 0.69 | FGFR1 (0.62) | FGFR1SRCPDGFRBPDGFRAABL1 | |
| SCHEMBL10323628 | 0.69 | DYRK1A (0.68) | — | |
| SCHEMBL3458816 | 0.68 | SRC (1.00) | FGFR1SRCPDGFRBSLC2A1PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | disclosed |