Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.37 |
| ▸ | FAAH | O00519 | 5/20 | 0.37 |
| ▸ | PLK1 | P53350 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12935186 | 0.94 | FAAH (0.40) | PTGS2FAAHPLK1HPGD | |
| SCHEMBL12935202 | 0.93 | PTGS2 (0.41) | PTGS2FAAHPLK1HPGD | |
| Hydrochloric Acid SCHEMBL2085142 | 0.93 | FAAH (0.40) | PTGS2FAAHPLK1HPGD | |
| Hydrochloric Acid SCHEMBL2083163 | 0.92 | PTGS2 (0.41) | PTGS2FAAHPLK1 | |
| SCHEMBL2084180 | 0.91 | CNR2 (0.40) | PTGS2FAAHPLK1HPGD | |
| SCHEMBL2083901 | 0.90 | CNR2 (0.39) | PTGS2FAAHPLK1HPGD | |
| SCHEMBL12935169 | 0.88 | FFAR1 (0.45) | PTGS2FAAHPLK1HPGDLTB4R2 | |
| Hydrochloric Acid SCHEMBL2085510 | 0.87 | FFAR1 (0.44) | PTGS2FAAHPLK1HPGDLTB4R2 | |
| SCHEMBL12935191 | 0.87 | FFAR1 (0.44) | PTGS2FAAHPLK1HPGD | |
| Hydrochloric Acid SCHEMBL2085709 | 0.86 | FFAR1 (0.43) | PTGS2FAAHPLK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781297-B1 | NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2008-10-15 | — | — | EP | disclosed |