Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.47 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637387 | 0.76 | KDM4E (0.69) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL32666100 | 0.76 | KDM4E (0.69) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11680789 | 0.75 | MAPT (0.54) | KDM4EMAPTLMNAHTTALDH1A1 | |
| SCHEMBL12856322 | 0.74 | XDH (0.62) | XDHKDM4EPOLBALDH1A1HPGD | |
| SCHEMBL1801401 | 0.70 | GAA (0.49) | AGPAT2TP53KDM4EMAPTLMNA | |
| SCHEMBL30289874 | 0.69 | MAPT (0.58) | KDM4EMAPTPOLBALDH1A1HPGD | |
| SCHEMBL30186672 | 0.68 | ADORA2A (0.52) | AGPAT2TP53CLK4 | |
| SCHEMBL2326699 | 0.68 | MEN1 (0.56) | AGPAT2TP53KDM4EMAPTLMNA | |
| SCHEMBL19690815 | 0.67 | POLA1 (0.48) | MAPTLMNAPOLBHTT | |
| SCHEMBL16986307 | 0.66 | MAPT (0.49) | KDM4EMAPTLMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1975620-A2 | Three hybrid assay system | GPC Biotech AG (DE) | 2008-10-01 | — | — | EP | disclosed |