Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799381 | 0.94 | GAA (0.45) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1802125 | 0.89 | ALDH1A1 (0.56) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1802347 | 0.76 | DYRK1A (0.48) | GAAKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1803640 | 0.74 | ALDH1A1 (0.58) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6682618 | 0.72 | EGFR (0.49) | TP53TRPA1MKNK1MKNK2 | |
| SCHEMBL3411336 | 0.72 | ABL1 (0.54) | GAAKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL1801663 | 0.71 | KDM4E (0.53) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1802588 | 0.71 | ALDH1A1 (0.53) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14040937 | 0.70 | XDH (0.47) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL19927642 | 0.69 | RPS6KA5 (0.49) | GAAKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011619-B2 | DYEING COMPOSITION FOR KERATIN FIBRES | OREAL (FR) | 2012-07-04 | — | — | EP | claimed |
| EP-1345580-B9 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND | OREAL (FR) | 2009-11-25 | — | — | EP | claimed |
| EP-1345580-B1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND | OREAL (FR) | 2006-06-07 | — | — | EP | claimed |
| EP-1011619-B1 | DYEING COMPOSITION FOR KERATIN FIBRES | OREAL (FR) | 2005-09-14 | — | — | EP | claimed |
| EP-1345579-B1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING AN AMINO PYRAZOLE AND A MINERAL COMPOUND | OREAL (FR) | 2005-06-29 | — | — | EP | claimed |
| US-20040237219-A1 | Composition for oxidation dyeing of keratinous fibres comprising at least a 4,5 or 3,4-diamino pyrazole or a triamino pyrazole and at least a particular cellulose compound, and dyeing method | L'OREAL (FR) | 2004-12-02 | — | — | US | claimed |
| US-6780203-B1 | DIAMINOPYRAZOLE DERIVATIVE OXIDATION HAIR DYE AND 3-AMINO-2-CHLORO-6- METHYLPHENOL OR SALT COUPLER | L'ORéAL S.A. (FR) | 2004-08-24 | — | — | US | claimed |
| US-20040088800-A1 | Composition for the oxidation dyeing of keratinous fibres comprising a diamino pyrazole and a carbonyl compound | L'OREAL (FR) | 2004-05-13 | — | — | US | claimed |
| US-20040074014-A1 | Composition for oxidation dyeing of keratinous fibres comprising an amino pyrazole and a mineral compound | L'OREAL (FR) | 2004-04-22 | — | — | US | claimed |
| EP-1404288-A2 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A AMINO PYRAZOLE AND A CELLULOSE COMPOUND | L'OREAL (FR) | 2004-04-07 | — | — | EP | claimed |
| WO-2002051373-A1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND | L'OREAL (FR) | 2002-07-04 | — | — | WO | claimed |
| WO-2002051371-A1 | COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING AN AMINO PYRAZOLE AND A MINERAL COMPOUND | L'OREAL (FR) | 2002-07-04 | — | — | WO | claimed |
| US-20020050013-A1 | Composition for dyeing keratin fibers which contain at least one diaminopyrazole, dyeing process, novel diaminopyrazoles and process for their preparation | L'OREAL | 2002-05-02 | — | — | US | claimed |
| WO-2001034104-A1 | COLOURING AGENT FOR KERATIN CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-05-17 | — | — | WO | claimed |
| US-6099592-A | SPECIFIED 3-SUBSTITUTED 4,5-DIAMINOPYRAZOLES SUCH AS 1-BENZYL-4,5-DIAMINO-3-METHYLPYRAZOLE AS OXIDATION DYE PRECURSORS; USE TO OBTAIN DYE COMPOSITIONS LEADING TO STRONG COLORATIONS, IN SHADES RANGING FROM RED TO BLUE | L'OREAL (FR) | 2000-08-08 | — | — | US | claimed |
| EP-1011619-A1 | DYEING COMPOSITION FOR KERATIN FIBRES | L'OREAL (FR) | 2000-06-28 | — | — | EP | claimed |
| WO-1999011231-A1 | DYEING COMPOSITION FOR KERATIN FIBRES | L'OREAL (FR) | 1999-03-11 | — | — | WO | claimed |
| EP-0740931-B1 | Compositions for dyeing keratinic fibers containing diaminopyrazoles, process for dyeing, diaminopyrazoles and process for their preparation | OREAL (FR) | 1997-08-20 | — | — | EP | claimed |
| WO-1996034591-A1 | DIAMINOPYRAZOLE-CONTAINING COMPOSITIONS FOR COLOURING KERATIN FIBRES, COLOURING PROCESS, NOVEL DIAMINOPYRAZOLES AND METHOD FOR THEIR PREPARATION | L'OREAL (FR) | 1996-11-07 | — | — | WO | claimed |
| EP-0740931-A1 | Compositions for dyeing keratinic fibers containing diaminopyrazoles, process for dyeing, diaminopyrazoles and process for their preparation | L'OREAL (FR) | 1996-11-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020050013-A1 | Composition for dyeing keratin fibers which contain at least one diaminopyrazole, dyeing process, novel diaminopyrazoles and process for their preparation | KRT18, DSP, TUBB3 | GAA 3834/4885KDM4E 723/4885ALDH1A1 653/4885 |
| US-20040237219-A1 | Composition for oxidation dyeing of keratinous fibres comprising at least a 4,5 or 3,4-diamino pyrazole or a triamino pyrazole and at least a particular cellulose compound, and dyeing method | KRT18, TUBB3, PPOX | GAA 4474/4885KDM4E 976/4885ALDH1A1 410/4885 |
| US-20040074014-A1 | Composition for oxidation dyeing of keratinous fibres comprising an amino pyrazole and a mineral compound | KRT18, TUBB3, COX5A | GAA 4669/4885KDM4E 1192/4885ALDH1A1 706/4885 |
| US-20040088800-A1 | Composition for the oxidation dyeing of keratinous fibres comprising a diamino pyrazole and a carbonyl compound | KRT18, TUBB3, COX5A | GAA 4579/4885KDM4E 1186/4885ALDH1A1 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.