Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.35 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.35 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.35 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14040973 | 0.84 | BLM (0.43) | THRBNPSR1L3MBTL1LMNA | |
| SCHEMBL14040795 | 0.81 | TACR1 (0.47) | HTTNPSR1ALDH1A1HPGDKMT2A | |
| SCHEMBL7972671 | 0.78 | TACR1 (0.51) | HTTALDH1A1HPGDKMT2ACNR1 | |
| SCHEMBL14040781 | 0.78 | SMN1; SMN2 (0.46) | NPSR1CNR1L3MBTL1LMNA | |
| SCHEMBL14040975 | 0.76 | BLM (0.46) | NPSR1L3MBTL1LMNA | |
| SCHEMBL7975013 | 0.71 | HPGD (0.56) | HTTALDH1A1HPGDKMT2AL3MBTL1 | |
| SCHEMBL7975015 | 0.71 | HPGD (0.56) | HTTALDH1A1HPGDKMT2AL3MBTL1 | |
| SCHEMBL7975009 | 0.71 | HPGD (0.56) | HTTALDH1A1HPGDKMT2AL3MBTL1 | |
| SCHEMBL8313063 | 0.69 | HRH1 (0.48) | KMT2AL3MBTL1 | |
| SCHEMBL9828176 | 0.69 | HRH1 (0.45) | NPSR1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318983-B1 | SUBSTITUTED IMIDAZOLES AS HISTAMINE H1 AND H3 AGONISTS OR ANTAGONISTS | SCHERING CORP (US) | 2008-10-22 | — | — | EP | disclosed |