Acetophenone

Acetophenone

SCHEMBL1404141

CC(=O)c1ccccc1.F

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
HPGD P15428 4/20 0.60
ALDH1A1 P00352 2/20 0.60
LMNA P02545 2/20 0.60
CES2 O00748 3/20 0.59
CES1 P23141 3/20 0.59
RAB9A P51151 2/20 0.56
NPC1 O15118 1/20 0.56
TAAR1 Q96RJ0 1/20 0.56
TSHR P16473 3/20 0.55
DAO P14920 1/20 0.55
NAPRT Q6XQN6 1/20 0.55
KMT2A Q03164 3/20 0.52
MEN1 O00255 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.50
POLB P06746 2/20 0.50
MAOB P27338 1/20 0.50
CYP3A4 P08684 1/20 0.50
PARP1 P09874 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetophenone SCHEMBL27462873 0.97 MAPT (0.71) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Acetophenone SCHEMBL16745259 0.97
Acetophenone SCHEMBL30537000 0.97
Acetophenone SCHEMBL737 0.97
Acetophenone SCHEMBL30537005 0.97
Acetophenone SCHEMBL719033 0.97 MAPT (0.71) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Acetophenone SCHEMBL1450855 0.97
Acetophenone SCHEMBL11876785 0.94 MAPT (0.68) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Acetophenone SCHEMBL11354178 0.94 MAPT (0.68) MAPTSMN1; SMN2HPGDALDH1A1LMNA
Acetophenone SCHEMBL4356164 0.94 MAPT (0.68) MAPTSMN1; SMN2HPGDALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107722146-A Method for producing solid polyaluminoxane composition 三井化学株式会社 2018-02-23 CN claimed
CN-119039127-A Fluorine-containing chalcone derivative 2' -fluorine chalcone, and preparation method and application thereof 兰州石化职业技术大学 2024-11-29 CN disclosed
CN-217646310-U Mixing arrangement is used in production of o-fluoro acetophenone 辽宁昊维科技有限公司 2022-10-25 CN disclosed
CN-217646310-U Mixing arrangement is used in production of o-fluoro acetophenone 辽宁昊维科技有限公司 2022-10-25 CN disclosed
CN-106478452-A CI-719 oxime derivatives and its application as FXR antagonist 上海医药工业研究院 2017-03-08 CN disclosed
EP-2291415-B1 CATALYSTS FOR PREPARING CIS 1,4-POLYDIENES BRIDGESTONE CORP (JP) 2016-07-20 EP disclosed
US-8664343-B2 Catalysts for preparing cis 1,4-polydienes BRIDGESTONE CORPORATION (JP) 2014-03-04 US disclosed
US-20110184137-A1 CATALYSTS FOR PREPARING CIS 1,4-POLYDIENES BRIDGESTONE CORPORATION (JP) 2011-07-28 US disclosed
EP-2291415-A2 CATALYSTS FOR PREPARING CIS 1,4-POLYDIENES Bridgestone Corporation (JP) 2011-03-09 EP disclosed
US-7820580-B2 Nickel-based catalysts for preparing high cis 1,4-polydienes BRIDGESTONE CORPORATION (JP) 2010-10-26 US disclosed
US-6596825-B1 Process for forming a high-cis polydiene. The process includes catalyzing a diene polymerization, and terminating the polymerization with an amine-water termination mixture, preferably a TMEDA-water termination mixture. The catalyst FIRESTONE POLYMERS, LLC 2003-07-22 US disclosed
EP-0980878-A1 Molecular weight regulation of cis-1,4-polybutadiene using carboxylates Bridgestone Corporation (JP) 2000-02-23 EP disclosed
US-5955553-A Molecular weight regulation of cis-1,4-polybutadiene using carboxylates BRIDGESTONE CORPORATION (US) 1999-09-21 US disclosed
US-5698643-A USING COORDINATION CATALYST; TIRES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-12-16 US disclosed
US-4983695-A Catalysis with nickel carboxylate, trialkylaluminum, and hydrogen fluoride ether complex THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-01-08 US disclosed
EP-0093075-B1 PREPARATION OF HIGH CIS-1,4-POLYBUTADIENE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-12-30 EP disclosed
EP-0093073-A1 Molecular weight control of polybutadiene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-02 EP disclosed
EP-0093075-A1 Preparation of high cis-1,4-polybutadiene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-02 EP disclosed
EP-0093074-A1 Controlling the molecular weight of polybutadiene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-02 EP disclosed
US-4383097-A USING NONCONJUGATED DIOLEFINS HAVING TRANS CONFIGURATION AND A CATALYST OF AN ORGANO ALUMINUM-NICKEL-FLUORINE COMPLEY THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-05-10 US disclosed