Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.57 |
| ▸ | MMP2 | P08253 | 5/20 | 0.57 |
| ▸ | MMP9 | P14780 | 5/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14042453 | 0.95 | HDAC3 (0.51) | MMP1MMP2MMP9EGFRSMN1; SMN2 | |
| SCHEMBL14041941 | 0.91 | MMP1 (0.58) | MMP1MMP2MMP9EGFRSMN1; SMN2 | |
| SCHEMBL14042109 | 0.88 | SMN1; SMN2 (0.45) | MMP1MMP2MMP9EGFRSMN1; SMN2 | |
| SCHEMBL14042090 | 0.87 | CA12 (0.49) | MMP1MMP2MMP9EGFRSMN1; SMN2 | |
| SCHEMBL14041966 | 0.86 | NPC1 (0.47) | MMP1MMP2MMP9SMN1; SMN2KMT2A | |
| SCHEMBL14042091 | 0.86 | SAE1 (0.48) | MMP1MMP2MMP9SMN1; SMN2KMT2A | |
| SCHEMBL14042123 | 0.85 | CYP3A4 (0.45) | MMP1MMP2MMP9EGFRSMN1; SMN2 | |
| SCHEMBL14042489 | 0.85 | TAS1R3 (0.47) | MMP1MMP2MMP9EGFRSMN1; SMN2 | |
| SCHEMBL14042128 | 0.85 | TAS1R3 (0.43) | MMP1MMP2MMP9SMN1; SMN2KMT2A | |
| SCHEMBL14042089 | 0.85 | KDM4E (0.48) | MMP1MMP2MMP9EGFRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | disclosed |