Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.67 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.61 |
| ▸ | KIT | P10721 | 2/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | LCK | P06239 | 3/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.59 |
| ▸ | BRAF | P15056 | 6/20 | 0.59 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.58 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | EPHB2 | P29323 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | ESYT2 | A0FGR8 | 1/20 | 0.52 |
| ▸ | HACL2 | A1L0T0 | 1/20 | 0.52 |
| ▸ | NBAS | A2RRP1 | 1/20 | 0.52 |
| ▸ | GTPBP10 | A4D1E9 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14042252 | 0.95 | BRAF (0.66) | CSF1RMAPK14KITKDRLCK | |
| SCHEMBL4746517 | 0.88 | LCK (0.63) | CSF1RMAPK14KITKDRLCK | |
| SCHEMBL14042248 | 0.88 | BRAF (0.68) | CSF1RMAPK14KITKDRLCK | |
| SCHEMBL14042471 | 0.87 | LCK (0.65) | CSF1RMAPK14KITKDRLCK | |
| SCHEMBL14042454 | 0.87 | CSNK1D (0.66) | CSF1RMAPK14KITKDRLCK | |
| SCHEMBL14042259 | 0.86 | BRAF (0.62) | CSF1RMAPK14KITLCKSRC | |
| SCHEMBL4863711 | 0.86 | LCK (0.57) | CSF1RMAPK14KITKDRLCK | |
| SCHEMBL14042261 | 0.86 | LCK (0.57) | CSF1RMAPK14KITKDRLCK | |
| SCHEMBL14042254 | 0.85 | LCK (0.56) | CSF1RMAPK14KITKDRLCK | |
| SCHEMBL14042467 | 0.84 | LCK (0.61) | CSF1RMAPK14KITKDRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124393-A1 | BENZOTHIAZOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-10-16 | — | — | WO | disclosed |