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Sugi Predict / Compounds / SCHEMBL1404239

SCHEMBL1404239

SCHEMBL1404239

CC(C)(C)OC(=O)N1CCC(NC(=O)OCC2c3ccccc3-c3ccccc32)(C(=O)O)CC1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 1/20 0.48
▸ KDM4E B2RXH2 1/20 0.41
▸ PKM P14618 1/20 0.41
▸ DPP8 Q6V1X1 1/20 0.41
▸ DPP9 Q86TI2 1/20 0.41
▸ EPHX2 P34913 1/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ TSHR P16473 2/20 0.41
▸ ALOX15 P16050 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ GPR119 Q8TDV5 1/20 0.40
▸ STS P08842 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30202258 1.00 BACE1 (0.48) BACE1KDM4EPKMDPP8DPP9
SCHEMBL12869622 0.94 BACE1 (0.45) BACE1KDM4EPKMDPP8DPP9
SCHEMBL14508508 0.94 BACE1 (0.45) BACE1KDM4EPKMDPP8DPP9
SCHEMBL1764254 0.93 BACE1 (0.43) BACE1KDM4EPKMDPP8DPP9
SCHEMBL5192807 0.91 BACE1 (0.46) BACE1KDM4EPKMDPP8DPP9
SCHEMBL31515070 0.91 BACE1 (0.46) BACE1KDM4EPKMDPP8DPP9
SCHEMBL1404235 0.91 EPHX2 (0.46) BACE1DPP8DPP9EPHX2KMT2A
SCHEMBL9281160 0.90 BACE1 (0.46) BACE1KDM4EPKMDPP8DPP9
SCHEMBL31377147 0.90 BACE1 (0.46) BACE1KDM4EPKMDPP8DPP9
SCHEMBL555165 0.89 BACE1 (0.44) BACE1KDM4EPKMDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878622-B Green chemical synthesis method of illegal stand 中肽生化有限公司 2026-02-27 — — CN claimed
CN-118878622-A Green chemical synthesis method of illegal stand 中肽生化有限公司 2024-11-01 — — CN claimed
CN-118878622-B Green chemical synthesis method of illegal stand 中肽生化有限公司 2026-02-27 — — CN disclosed
US-20260001928-A1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY CORTERIA PHARMACEUTICALS (FR) 2026-01-01 — — US disclosed
EP-4482578-B1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY CORTERIA PHARMACEUTICALS (FR) 2025-12-24 — — EP disclosed
US-20250353854-A1 FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF MENIN BIOMEA FUSION INC (US) 2025-11-20 — — US disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 — — US disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
US-20250084012-A1 METHOD FOR REMOVING TERT-BUTOXYCARBONYL GROUP CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-03-13 — — US disclosed
CN-119569644-A Small molecule compound as GPR34 regulator 四川大学 2025-03-07 — — CN disclosed
EP-4482578-A1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY Corteria Pharmaceuticals (FR) 2025-01-01 — — EP disclosed
US-6720338-B2 BCL-X1 INHIBITING COMPOSITIONS AND METHODS OF PROMOTING APOPTOSIS IN A MAMMAL ABBOTT LABORATORIES 2004-04-13 — — US disclosed
US-6713580-B2 CYCLIZED AMINO ACIDS ARE COUPLED TO A POLYSTYRENE DERIVATIVE FOR USE IN SYNTHESIS OF PEPTIDES AND OF AMINO ACID CONTAINING COMPOUNDS FOR DRUG DISCOVERY PHARMACORE, INC. 2004-03-30 — — US disclosed
US-20040059088-A1 Short amphipathic peptides with activity against bacteria and intracellular pathogens MCLAUGHLIN MARK L (US) 2004-03-25 — — US disclosed
EP-1373195-A2 QUATERNARY AMINO ACIDS ON SOLID SUPPORTS PharmaCore, Inc, (US) 2004-01-02 — — EP disclosed
US-6566334-B1 For therapy of bacterial infection BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE 2003-05-20 — — US disclosed
US-20020086887-A1 N-Acylsulfonamide apoptosis promoters ABBVIE INC. 2002-07-04 — — US disclosed
US-20020086949-A1 Cyclized amino acids are coupled to a polystyrene derivative for use in synthesis of peptides and of amino acid containing compounds for drug discovery PHARMACORE, INC. 2002-07-04 — — US disclosed
WO-2002046128-A2 QUATERNARY AMINO ACIDS ON SOLID SUPPORTS PHARMACORE, INC. (US) 2002-06-13 — — WO disclosed
US-20020055631-A1 N-acylsulfonamide apoptosis promoters ABBOTT LABORATORIES 2002-05-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020086887-A1 N-Acylsulfonamide apoptosis promoters BAX, BCLAF1, BCL2 BACE1 1508/4885KDM4E 1911/4885PKM 4646/4885
US-20020055631-A1 N-acylsulfonamide apoptosis promoters BAX, BCLAF1, BCL2 BACE1 2176/4885KDM4E 1563/4885PKM 4553/4885
US-20250084012-A1 METHOD FOR REMOVING TERT-BUTOXYCARBONYL GROUP TERT, MGMT, MITF BACE1 3565/4885KDM4E 1269/4885PKM 2815/4885
US-20040059088-A1 Short amphipathic peptides with activity against bacteria and intracellular pathogens VIP, MDK, HM13 BACE1 3873/4885KDM4E 4672/4885PKM 2163/4885
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS BACE1 1374/4885KDM4E 2083/4885PKM 2137/4885
US-20250353854-A1 FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF MENIN MEN1, MLLT1, MSI2 BACE1 3501/4885KDM4E 588/4885PKM 3271/4885
US-20260001928-A1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY GIPR, NPY2R, NPY1R BACE1 3564/4885KDM4E 1705/4885PKM 1129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.