SCHEMBL1404249

SCHEMBL1404249

CCOP(=O)(O)OCc1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.81
CETP P11597 4/20 0.57
SRC P12931 1/20 0.53
AKR1C3 P42330 1/20 0.49
FOLH1 Q04609 1/20 0.47
POLB P06746 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
PDPK1 O15530 1/20 0.45
MTOR P42345 1/20 0.45
NR1I2 O75469 1/20 0.45
ALPG P10696 1/20 0.45
PTK2B Q14289 1/20 0.45
KCNH2 Q12809 1/20 0.44
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL6037288 0.91 TSHR (0.85) TSHRCETPSRCAKR1C3FOLH1
SCHEMBL27908642 0.90 TSHR (1.00) TSHRCETPSRCAKR1C3FOLH1
SCHEMBL51316 0.90 TSHR (1.00) TSHRCETPSRCAKR1C3FOLH1
Hydrochloric Acid SCHEMBL10722992 0.88 TSHR (0.96) TSHRCETPSRCAKR1C3FOLH1
SCHEMBL11756554 0.88 TSHR (0.96) TSHRCETPSRCAKR1C3FOLH1
SCHEMBL28264490 0.88 TSHR (0.96) TSHRCETPSRCAKR1C3FOLH1
SCHEMBL4219700 0.88 TSHR (0.96) TSHRCETPSRCAKR1C3FOLH1
SCHEMBL9446520 0.88 TSHR (0.96) TSHRCETPSRCAKR1C3FOLH1
Ammonia Solution, Strong SCHEMBL7268743 0.88 TSHR (0.96) TSHRCETPSRCAKR1C3FOLH1
Phosphoric Acid SCHEMBL27741297 0.88 TSHR (0.96) TSHRCETPSRCAKR1C3FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2057217-B1 BARIUM SULFATE-CONTAINING COMPOSITE SACHTLEBEN CHEMIE GMBH (DE) 2017-02-22 EP claimed
CN-103173884-B A kind of halogen-free flame-retardant polypropylene fiber and preparation method thereof 上海杰事杰新材料(集团)股份有限公司 2016-08-24 CN claimed
WO-2010149571-A1 CHEMICAL FIBRE HAVING AN ADDITIVE FOR IMPROVING THE PHYSICAL PROPERTIES SACHTLEBEN CHEMIE GMBH (DE) 2010-12-29 WO claimed
US-7645334-B2 Barium sulfate SACHTLEBEN CHEMIE GMBH (DE) 2010-01-12 US claimed
US-20090326114-A1 BARIUM SULFATE-CONTAINING COMPOSITE SACHTLEBEN CHEMIE GMBH (DE) 2009-12-31 US claimed
US-20090318594-A1 BARIUM SULFATE-CONTAINING COMPOSITE SACHTLEBEN CHEMIE GMBH (DE) 2009-12-24 US claimed
US-20080314291-A1 Barium Sulfate SACHTLEBEN CHEMIE GMBH (DE) 2008-12-25 US claimed
EP-1989263-A1 BARIUM SULPHATE Sachtleben Chemie GmbH (DE) 2008-11-12 EP claimed
WO-2007096385-A1 BARIUM SULPHATE SACHTLEBEN CHEMIE GMBH (DE) 2007-08-30 WO claimed
WO-2024054618-A1 METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. (US) 2024-03-14 WO disclosed
WO-2023239665-A1 METHODS FOR TREATMENT OF VIRAL INFECTIONS INCLUDING SARS-COV-2 GILEAD SCIENCES, INC. (US) 2023-12-14 WO disclosed
US-20230279014-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. 2023-09-07 US disclosed
EP-4134098-A1 METHOD OF CANCER THERAPY ONO Pharmaceutical Co., Ltd. (JP) 2023-02-15 EP disclosed
EP-4134134-A1 STING AGONISTIC COMPOUND ONO Pharmaceutical Co., Ltd. (JP) 2023-02-15 EP disclosed
US-5026758-A Heat resistance, toughness BAYER AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed
EP-0419927-A1 Thermoplastic moulding compositions of polyalkylene terephthalate, specific barium sulfate, particulate graft polymers, and possibly reinforcing agents BAYER AG (DE) 1991-04-03 EP disclosed
EP-0416407-A1 Thermoplastic moulding compositions of polycarbonate, polyalkylene terephthalate, specific barium sulfate, and possibly elastomers BAYER AG (DE) 1991-03-13 EP disclosed
EP-0371530-A1 Process for manufacturing barium sulphate with a variable morphology METALLGESELLSCHAFT Aktiengesellschaft (DE) 1990-06-06 EP disclosed
EP-0335159-A1 Thermoplastic moulding compositions BAYER AG (DE) 1989-10-04 EP disclosed
EP-0293622-A1 Process for preparing barium sulphate having a chemically reactive surface METALLGESELLSCHAFT AG (DE) 1988-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230279014-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS HAVCR2, EIF2AK2, OAT TSHR 4522/4885CETP 727/4885SRC 1829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.