SCHEMBL1404261

SCHEMBL1404261

CCCC(CO)C(O)CC(C)CC

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP2D6 P10635 2/20 0.31
SPHK1 Q9NYA1 1/20 0.31
GMNN O75496 1/20 0.31
POLB P06746 1/20 0.31
THPO P40225 1/20 0.31
MTOR P42345 1/20 0.31
BLM P54132 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
CETP P11597 1/20 0.31
HTT P42858 1/20 0.31
UBE2N P61088 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL497879 0.86 LMNA (0.60) LMNATSHRTDP1
SCHEMBL3671978 0.84 LMNA (0.52) LMNATSHRTDP1CYP2D6SPHK1
SCHEMBL5154336 0.81 LMNA (0.65) LMNATSHRALDH1A1TDP1CYP2D6
SCHEMBL13757121 0.79 LMNA (0.61) LMNATSHRALDH1A1TDP1CYP2D6
SCHEMBL8757790 0.79 LMNA (0.76) LMNATSHRALDH1A1TDP1CYP2D6
SCHEMBL18961175 0.79 LMNA (0.61) LMNATSHRALDH1A1TDP1CYP2D6
SCHEMBL11294202 0.77 TSHR (0.42) LMNATSHRTDP1KDM4E
SCHEMBL8558834 0.77 LMNA (0.46) LMNATSHRSPHK1
SCHEMBL4889381 0.75 TSHR (0.47) LMNATSHRALDH1A1TDP1
SCHEMBL4893475 0.75 LMNA (0.42) LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023227539-A1 ONE-COMPONENT BURN-IN SYSTEM COVESTRO DEUTSCHLAND AG (DE) 2023-11-30 WO disclosed
WO-2023227540-A1 BLOCKED POLYISOCYANATES COVESTRO DEUTSCHLAND AG (DE) 2023-11-30 WO disclosed
EP-4282894-A1 SINGLE-COMPONENT STOVING SYSTEM Covestro Deutschland AG (DE) 2023-11-29 EP disclosed
EP-4282893-A1 BLOCKED POLYISOCYANATES Covestro Deutschland AG (DE) 2023-11-29 EP disclosed
EP-2291432-B1 USE OF A C11 DIOL OR C11 DIOL MIXTURE FOR PRODUCING POLYMERS BASF SE (DE) 2012-08-15 EP disclosed
EP-2291432-A1 USE OF A C11 DIOL OR C11 DIOL MIXTURE FOR PRODUCING POLYMERS BASF SE (DE) 2011-03-09 EP disclosed
WO-2009153193-A1 USE OF A C11 DIOL OR C11 DIOL MIXTURE FOR PRODUCING POLYMERS BASF SE (DE) 2009-12-23 WO disclosed