Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404257 | 0.97 | CA2 (0.34) | CA2CA1MAPK1CTSK | |
| SCHEMBL1404264 | 0.83 | CA2 (0.38) | CA2CA1MAPK1TSHRCTSK | |
| SCHEMBL5185206 | 0.83 | CA2 (0.41) | CA2CA1MAPK1TSHRCYP3A4 | |
| SCHEMBL2516488 | 0.83 | CA2 (0.42) | CA2CA1 | |
| SCHEMBL4726041 | 0.80 | CA2 (0.39) | CA2CA1MAPK1 | |
| SCHEMBL1404258 | 0.80 | CA2 (0.36) | CA2CA1MAPK1 | |
| SCHEMBL1404265 | 0.77 | CA2 (0.39) | CA2CA1MAPK1TSHRCYP3A4 | |
| SCHEMBL28456703 | 0.76 | CA2 (0.41) | CA2CA1MAPK1 | |
| SCHEMBL2516490 | 0.75 | GPR84 (0.43) | CA2MAPK1 | |
| SCHEMBL1404259 | 0.74 | CA2 (0.37) | CA2CA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2291430-A1 | METHODS FOR BRANCHING PHA USING THERMOLYSIS | METABOLIX, INC. (US) | 2011-03-09 | — | — | EP | claimed |
| WO-2010008447-A1 | METHODS FOR BRANCHING PHA USING THERMOLYSIS | METABOLIX, INC. (US) | 2010-01-21 | — | — | WO | claimed |