Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13515252 | 1.00 | STAT3 (0.40) | STAT3ALDH1A1LMNAMAPK1DHODH | |
| SCHEMBL8423991 | 0.91 | STAT3 (0.44) | STAT3ALDH1A1LMNAMAPK1DHODH | |
| SCHEMBL5473716 | 0.87 | STAT3 (0.41) | STAT3ALDH1A1LMNAMAPK1DHODH | |
| SCHEMBL5473718 | 0.87 | STAT3 (0.41) | STAT3ALDH1A1LMNAMAPK1DHODH | |
| SCHEMBL5473721 | 0.87 | STAT3 (0.41) | STAT3ALDH1A1LMNAMAPK1DHODH | |
| SCHEMBL9771979 | 0.86 | AR (0.41) | STAT3ALDH1A1LMNAMAPK1DHODH | |
| SCHEMBL13117673 | 0.86 | STAT3 (0.40) | STAT3ALDH1A1LMNAMAPK1DHODH | |
| SCHEMBL5471181 | 0.86 | AR (0.41) | STAT3ALDH1A1LMNAMAPK1DHODH | |
| SCHEMBL5475793 | 0.86 | AR (0.41) | STAT3ALDH1A1LMNAMAPK1DHODH | |
| SCHEMBL2938789 | 0.83 | STAT3 (0.38) | STAT3ALDH1A1LMNAMAPK1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124651-A2 | NITRO-IMIDAZOLE HYPOXIA IMAGING AGENTS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-10-16 | — | — | WO | disclosed |