Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2938792 | 1.00 | STAT3 (0.38) | STAT3GLAALDH1A1MAPK1LMNA | |
| SCHEMBL8423991 | 0.88 | STAT3 (0.44) | STAT3ALDH1A1MAPK1LMNADHODH | |
| SCHEMBL5473718 | 0.84 | STAT3 (0.41) | STAT3ALDH1A1MAPK1LMNADHODH | |
| SCHEMBL5473721 | 0.84 | STAT3 (0.41) | STAT3ALDH1A1MAPK1LMNADHODH | |
| SCHEMBL5473716 | 0.84 | STAT3 (0.41) | STAT3ALDH1A1MAPK1LMNADHODH | |
| SCHEMBL14042906 | 0.83 | STAT3 (0.40) | STAT3ALDH1A1MAPK1LMNADHODH | |
| SCHEMBL13117673 | 0.83 | STAT3 (0.40) | STAT3ALDH1A1MAPK1LMNADHODH | |
| SCHEMBL9771979 | 0.83 | AR (0.41) | STAT3ALDH1A1MAPK1LMNADHODH | |
| SCHEMBL5471181 | 0.83 | AR (0.41) | STAT3ALDH1A1MAPK1LMNADHODH | |
| SCHEMBL5475793 | 0.83 | AR (0.41) | STAT3ALDH1A1MAPK1LMNADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869199-B1 | A CHEMOENZYMATIC PROCESS FOR THE STEREOSELECTIVE PREPARATION OF (R)-GAMMA-AMINO-BETA-HYDROXYBUTYRIC ACID ((R) -GABOB) AND (R)-CARNITINE | COUNCIL SCIENT IND RES (IN) | 2010-01-06 | — | — | EP | claimed |
| US-7816119-B2 | Chemoenzymatic process for the stereoselective preparation of (R)-γ-amino-β-hydroxybutyric acid or (R)-carnitine from 3,4-dihydroxybutanenitrile | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-10-19 | — | — | US | disclosed |
| EP-1869199-B1 | A CHEMOENZYMATIC PROCESS FOR THE STEREOSELECTIVE PREPARATION OF (R)-GAMMA-AMINO-BETA-HYDROXYBUTYRIC ACID ((R) -GABOB) AND (R)-CARNITINE | COUNCIL SCIENT IND RES (IN) | 2010-01-06 | — | — | EP | disclosed |
| US-20090233337-A1 | Chemoenzymatic Process for the Stereoselective Preparation of (R)-Gamma-Amino-Beta-Hydroxybutyric Acid [(R)-GABOB) and (R)-Carnitine | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-17 | — | — | US | disclosed |