Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 5/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3495173 | 0.87 | MAPK8 (0.47) | MAPK8IKBKBHTR3EHTR3BHTR3A | |
| SCHEMBL17895234 | 0.84 | IKBKB (0.57) | MAPK8IKBKBHTR3EHTR3BHTR3A | |
| SCHEMBL8103067 | 0.79 | MAPK8 (0.73) | MAPK8IKBKBHTR3EHTR3BHTR3A | |
| SCHEMBL3498276 | 0.75 | KDM4E (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL17895304 | 0.75 | IKBKB (0.68) | MAPK8IKBKB | |
| SCHEMBL31746824 | 0.74 | ABL1 (0.43) | — | |
| SCHEMBL14044186 | 0.74 | IKBKB (0.42) | IKBKBLMNAMEN1KMT2ARXFP1 | |
| SCHEMBL3496156 | 0.73 | HTR3E (0.52) | MAPK8IKBKBHTR3EHTR3BHTR3A | |
| SCHEMBL31746683 | 0.72 | CNR1 (0.43) | MAPK8IKBKBKDM4ETP53LMNA | |
| SCHEMBL11500648 | 0.71 | MAPK8 (0.68) | MAPK8IKBKBHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117225-A2 | NEW IMIDAZOLO-HETEROARYL DERIVATIVES WITH ANTIBACTERIAL PROPERTIES | MUTABILIS SA (FR) | 2008-10-02 | — | — | WO | disclosed |