Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 12/20 | 0.41 |
| ▸ | PGR | P06401 | 9/20 | 0.41 |
| ▸ | CNR2 | P34972 | 8/20 | 0.37 |
| ▸ | CNR1 | P21554 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227227 | 0.91 | NR3C2 (0.50) | NR3C1NR3C2PGR | |
| SCHEMBL3220337 | 0.83 | NR3C1 (0.53) | NR3C1NR3C2PGR | |
| SCHEMBL3228274 | 0.80 | NR3C1 (0.61) | NR3C1NR3C2PGR | |
| SCHEMBL3224738 | 0.80 | NR3C2 (0.52) | NR3C1NR3C2PGRCNR2 | |
| SCHEMBL3219833 | 0.78 | NR3C2 (0.52) | NR3C1NR3C2PGR | |
| SCHEMBL3214313 | 0.77 | NR3C1 (0.54) | NR3C1NR3C2PGR | |
| SCHEMBL14044318 | 0.74 | NR3C2 (0.40) | NR3C1NR3C2PGR | |
| SCHEMBL14044355 | 0.74 | NR3C1 (0.52) | NR3C1NR3C2PGR | |
| SCHEMBL3229138 | 0.73 | NR3C1 (0.57) | NR3C1NR3C2PGR | |
| SCHEMBL3229621 | 0.72 | NR3C1 (0.58) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124745-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | WO | disclosed |