Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14044948 | 0.92 | F10 (0.46) | F10LMNAMAPK1KMT2AF2 | |
| SCHEMBL3310232 | 0.92 | F10 (0.46) | F10LMNAMAPK1KMT2AF2 | |
| SCHEMBL13394894 | 0.90 | MMP2 (0.46) | F10LMNAMAPK1KMT2AMMP2 | |
| SCHEMBL8489431 | 0.89 | F10 (0.44) | F10LMNAMAPK1KMT2AF2 | |
| SCHEMBL13394931 | 0.89 | F10 (0.44) | F10LMNAMAPK1KMT2AF2 | |
| SCHEMBL4583776 | 0.89 | F10 (0.45) | F10LMNAMAPK1KMT2AF2 | |
| SCHEMBL8489145 | 0.89 | F10 (0.45) | F10LMNAMAPK1KMT2AF2 | |
| SCHEMBL13394885 | 0.87 | MMP2 (0.48) | F10LMNAMAPK1KMT2AF2 | |
| SCHEMBL13394941 | 0.86 | F10 (0.43) | F10LMNAMAPK1KMT2AF2 | |
| SCHEMBL13394928 | 0.86 | F10 (0.44) | F10LMNAMAPK1KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116881-A1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-02 | — | — | WO | disclosed |