SCHEMBL8489145 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	14/20	0.45

▸	LMNA	P02545	1/20	0.42

▸	MAPK1	P28482	1/20	0.42

▸	KMT2A	Q03164	1/20	0.42

▸	F2	P00734	2/20	0.39

▸	MMP2	P08253	2/20	0.38

▸	ANPEP	P15144	1/20	0.38

▸	MCHR1	Q99705	2/20	0.35

▸	F11	P03951	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4583776	1.00	F10 (0.45)	F10LMNAMAPK1KMT2AF2
SCHEMBL3310232	0.97	F10 (0.46)	F10LMNAMAPK1KMT2AF2
SCHEMBL14044948	0.97	F10 (0.46)	F10LMNAMAPK1KMT2AF2
SCHEMBL13394885	0.91	MMP2 (0.48)	F10LMNAMAPK1KMT2AF2
SCHEMBL3314623	0.91	F10 (0.42)	F10LMNAMAPK1KMT2AF2
SCHEMBL13394928	0.90	F10 (0.44)	F10LMNAMAPK1KMT2AF2
SCHEMBL13394894	0.89	MMP2 (0.46)	F10LMNAMAPK1KMT2AMMP2
SCHEMBL14045006	0.89	F10 (0.44)	F10LMNAMAPK1KMT2AF2
SCHEMBL13394931	0.88	F10 (0.44)	F10LMNAMAPK1KMT2AF2
SCHEMBL8489431	0.88	F10 (0.44)	F10LMNAMAPK1KMT2AF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1975165-A1	Substituted pyrrolidinamides, their production and utilisation as medicine	Boehringer Ingelheim Pharma GmbH & Co. KG (DE)	2008-10-01	—	—	EP	disclosed