Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592409 | 0.98 | TP53 (0.47) | THRBTP53SLC6A3ALDH1A1NPSR1 | |
| SCHEMBL3996792 | 0.98 | TP53 (0.47) | THRBTP53SLC6A3ALDH1A1NPSR1 | |
| SCHEMBL28755738 | 0.95 | THRB (0.46) | THRBTP53SLC6A3ALDH1A1NPSR1 | |
| SCHEMBL1485389 | 0.91 | — | — | |
| SCHEMBL11117724 | 0.81 | EPHX1 (0.39) | THRBTP53ALDH1A1SMN1; SMN2ADRB2 | |
| SCHEMBL18307376 | 0.81 | SLC6A3 (0.46) | THRBSLC6A3ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL18502891 | 0.79 | TP53 (0.47) | THRBTP53SLC6A3ALDH1A1KMT2A | |
| SCHEMBL4491334 | 0.79 | THRB (0.61) | THRBTP53SLC6A3ALDH1A1NPSR1 | |
| SCHEMBL15821270 | 0.79 | EPHX1 (0.38) | THRBTP53ALDH1A1SMN1; SMN2ADRB2 | |
| SCHEMBL12687878 | 0.78 | TP53 (0.36) | THRBTP53SLC6A3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261118-A1 | OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM | FUJIFILM CORPORATION (JP) | 2008-10-23 | — | — | US | disclosed |