Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13654099 | 0.86 | MAOB (0.38) | MAOBMAOANPC1MAPTRAB9A | |
| SCHEMBL13654100 | 0.81 | L3MBTL1 (0.46) | MAOBMAOANPC1MAPTRAB9A | |
| SCHEMBL13531014 | 0.70 | KMT2A (0.51) | MAOBMAOANPC1MAPTRAB9A | |
| SCHEMBL13654072 | 0.70 | MAOB (0.41) | MAOBMAOANPC1MAPTRAB9A | |
| SCHEMBL13529582 | 0.69 | RAB9A (0.40) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL3176672 | 0.68 | CYSLTR1 (0.45) | NPC1RAB9APOLBSMN1; SMN2KMT2A | |
| SCHEMBL3176676 | 0.68 | CYSLTR1 (0.45) | NPC1RAB9APOLBSMN1; SMN2KMT2A | |
| SCHEMBL13529854 | 0.67 | PPARA (0.43) | — | |
| SCHEMBL13531068 | 0.67 | PPARA (0.41) | — | |
| SCHEMBL16198944 | 0.66 | MAPT (0.40) | MAOBNPC1MAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |