SCHEMBL14045541

SCHEMBL14045541

CN[C@H]1C[C@@H]2O[C@@]3(c4cccc5c6c7c(c8c9ccccc9n2c8c6n3c45)C(=O)NC7)[C@H]1OC

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRKCQ Q04759 13/20 0.75
▸ PRKCZ Q05513 9/20 0.75
▸ PRKD3 O94806 8/20 0.75
▸ PRKCG P05129 8/20 0.75
▸ PRKCD Q05655 8/20 0.75
▸ ROCK2 O75116 7/20 0.75
▸ PRKCB P05771 7/20 0.75
▸ PRKCA P17252 7/20 0.75
▸ PRKCH P24723 7/20 0.75
▸ PRKCI P41743 7/20 0.75
▸ PRKCE Q02156 7/20 0.75
▸ PRKD1 Q15139 7/20 0.75
▸ EGFR P00533 5/20 0.75
▸ PRKACA P17612 5/20 0.75
▸ KDR P35968 4/20 0.75
▸ SRC P12931 4/20 0.75
▸ PRKACG P22612 4/20 0.75
▸ PRKACB P22694 4/20 0.75
▸ CHEK1 O14757 3/20 0.75
▸ MAPK1 P28482 3/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272173 1.00 PRKCQ (0.75) PRKCQPRKCZPRKD3PRKCGPRKCD
SCHEMBL19492755 1.00 PRKCQ (0.75) PRKCQPRKCZPRKD3PRKCGPRKCD
Staurosporine SCHEMBL23768489 0.86 PRKCQ (1.00) PRKCQPRKCZPRKD3PRKCGPRKCD
Staurosporine SCHEMBL13168061 0.86 PRKCQ (1.00) PRKCQPRKCZPRKD3PRKCGPRKCD
Staurosporine SCHEMBL13621639 0.86 PRKCQ (1.00) PRKCQPRKCZPRKD3PRKCGPRKCD
Staurosporine SCHEMBL23793206 0.86 PRKCQ (1.00) PRKCQPRKCZPRKD3PRKCGPRKCD
SCHEMBL12304513 0.86 PRKCQ (1.00) PRKCQPRKCZPRKD3PRKCGPRKCD
SCHEMBL24393902 0.86 PRKCQ (1.00) PRKCQPRKCZPRKD3PRKCGPRKCD
Staurosporine SCHEMBL21312855 0.86 PRKCQ (1.00) PRKCQPRKCZPRKD3PRKCGPRKCD
Staurosporine SCHEMBL12430819 0.86 PRKCQ (1.00) PRKCQPRKCZPRKD3PRKCGPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080268058-A1 including a polymer including vinyl formal monomer units; includes a cavity that is defined by the matrix and that has a maximum dimension of from 10 microns to 1,000 microns; can be used to deliver one or more chemotherapeutic agents to a target site BOSTON SCIENTIFIC SCIMED, INC. (US) 2008-10-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080268058-A1 including a polymer including vinyl formal monomer units; includes a cavity that is defined by the matrix and that has a maximum dimension of from 10 microns to 1,000 microns; can be used to deliver one or more chemotherapeutic agents to a target site VCL, MTHFD1, VMP1 PRKCQ 4050/4885PRKCZ 3445/4885PRKD3 4399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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