Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.31 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028703 | 0.71 | MAPK1 (0.37) | MEN1MAPK1KMT2A | |
| SCHEMBL2636397 | 0.63 | MEN1 (0.60) | MEN1MAPK1KMT2A | |
| SCHEMBL2636394 | 0.63 | MEN1 (0.60) | MEN1MAPK1KMT2A | |
| SCHEMBL2328170 | 0.61 | KMT2A (0.57) | MEN1MAPK1KMT2A | |
| SCHEMBL2328166 | 0.61 | KMT2A (0.57) | MEN1MAPK1KMT2A | |
| SCHEMBL21215222 | 0.58 | KDM1A (0.60) | MEN1MAPK1KMT2A | |
| SCHEMBL12291730 | 0.56 | PRSS1 (0.46) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL13094278 | 0.55 | F2 (0.59) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL1334368 | 0.55 | KMT2A (0.45) | MEN1MAPK1KMT2A | |
| SCHEMBL1334373 | 0.55 | KMT2A (0.45) | MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432278-B2 | Dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2008-10-07 | — | — | US | disclosed |