Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 3/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL4952305 | 0.86 | ITGB3 (0.41) | ITGB3ITGA2BWDR5 | |
| SCHEMBL4950301 | 0.77 | LMNA (0.42) | KMT2ALMNANPC1HTTRAB9A | |
| Acetic Acid SCHEMBL4952218 | 0.72 | ITGB3 (0.41) | LMNANPC1HTTRAB9AITGB3 | |
| SCHEMBL14046570 | 0.71 | MEN1 (0.39) | MAPK1MEN1KMT2A | |
| SCHEMBL4951689 | 0.69 | WDR5 (0.38) | LMNANPC1HTTRAB9AITGB3 | |
| SCHEMBL14028701 | 0.69 | ALDH1A3 (0.51) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL4947968 | 0.67 | NQO2 (0.47) | ALDH1A1 | |
| SCHEMBL14028700 | 0.66 | WDR5 (0.50) | MEN1KMT2ALMNANPC1HTT | |
| Acetic Acid SCHEMBL4951340 | 0.65 | NQO2 (0.40) | LMNANPC1HTTRAB9AITGB3 | |
| Acetic Acid SCHEMBL4952431 | 0.63 | NQO2 (0.53) | NPC1ITGB3ITGA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432278-B2 | Dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2008-10-07 | — | — | US | disclosed |