Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221440 | 0.88 | TSHR (0.48) | TSHRCHRNB2CHRNA4IDO1SLC1A3 | |
| SCHEMBL28576014 | 0.81 | SLC1A3 (0.42) | TSHRCHRNB2CHRNA4IDO1SLC1A3 | |
| SCHEMBL871423 | 0.81 | TSHR (0.41) | TSHRCHRNB2CHRNA4IDO1SLC1A3 | |
| SCHEMBL6379469 | 0.81 | SLC1A3 (0.42) | TSHRCHRNB2CHRNA4IDO1SLC1A3 | |
| SCHEMBL4007775 | 0.80 | MAOB (0.39) | TSHRCHRNB2CHRNA4IDO1SLC1A3 | |
| SCHEMBL4007778 | 0.80 | MAOB (0.39) | TSHRCHRNB2CHRNA4IDO1SLC1A3 | |
| SCHEMBL6884652 | 0.77 | SLC1A3 (0.39) | TSHRCHRNB2CHRNA4IDO1SLC1A3 | |
| SCHEMBL31697649 | 0.75 | TSHR (0.48) | TSHRCHRNB2CHRNA4IDO1SLC1A3 | |
| SCHEMBL10338112 | 0.74 | ADRB2 (0.40) | TSHRCYP2D6ALDH1A1 | |
| SCHEMBL10338108 | 0.74 | ADRB2 (0.40) | TSHRCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269342-A1 | Pleuromutilin Derivatives and Its Use | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269342-A1 | Pleuromutilin Derivatives and Its Use | PLEC, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, IL17A | TSHR 625/4885CHRNB2 4590/4885CHRNA4 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.