Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047494 | 0.82 | PIK3CD (0.36) | MEN1KMT2AMAPTMAPK1PIK3CD | |
| SCHEMBL5302 | 0.80 | GPR139 (0.39) | MEN1KMT2AMAPTPIK3CDGPR139 | |
| SCHEMBL21445289 | 0.74 | TP53 (0.42) | SMN1; SMN2MEN1KMT2APOLBMAPT | |
| SCHEMBL4181164 | 0.72 | CTSA (0.42) | MEN1KMT2APIK3CDPIK3CG | |
| SCHEMBL844461 | 0.70 | MAPT (0.46) | SMN1; SMN2MEN1KMT2APOLBMAPT | |
| SCHEMBL4178733 | 0.70 | CTSA (0.45) | MEN1KMT2A | |
| SCHEMBL4178743 | 0.70 | PIK3CD (0.37) | KMT2APIK3CD | |
| SCHEMBL4182711 | 0.70 | PIK3CD (0.37) | KMT2APIK3CD | |
| SCHEMBL29683769 | 0.70 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL9791867 | 0.70 | ERN1 (0.47) | MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118468-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2008-10-02 | — | — | WO | disclosed |