Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 12/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047579 | 0.83 | HDAC1 (0.50) | HDAC1SCD | |
| SCHEMBL14047539 | 0.79 | SCD (0.53) | HDAC1SCDKMT2A | |
| SCHEMBL14047421 | 0.79 | SCD (0.59) | HDAC1SCDKMT2AP2RX7 | |
| SCHEMBL14047603 | 0.78 | SCD (0.57) | SCDKMT2A | |
| SCHEMBL14047400 | 0.78 | SCD (0.57) | HDAC1SCDKMT2A | |
| SCHEMBL14047625 | 0.78 | SCD (0.57) | HDAC1SCDKMT2A | |
| SCHEMBL14047404 | 0.78 | SCD (0.47) | HDAC1SCD | |
| SCHEMBL14047595 | 0.77 | SCD (0.56) | HDAC1SCD | |
| SCHEMBL244560 | 0.77 | SCD (0.64) | HDAC1SCD | |
| SCHEMBL14047409 | 0.76 | SCD (0.47) | HDAC1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127349-A2 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | disclosed |