Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 6/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047595 | 0.95 | SCD (0.56) | SCDCACNA1GCACNA1HCACNA1IHPGD | |
| SCHEMBL14047625 | 0.94 | SCD (0.57) | SCDCACNA1GCACNA1HCACNA1IHPGD | |
| SCHEMBL14047400 | 0.94 | SCD (0.57) | SCDCACNA1GCACNA1HCACNA1IHPGD | |
| SCHEMBL14047603 | 0.91 | SCD (0.57) | SCDCACNA1GCACNA1HCACNA1IALDH1A1 | |
| SCHEMBL14047581 | 0.88 | ALDH1A1 (0.45) | SCDCACNA1GCACNA1HCACNA1IHPGD | |
| SCHEMBL14047531 | 0.88 | SCD (0.41) | SCDCACNA1GCACNA1HCACNA1IHPGD | |
| SCHEMBL14047407 | 0.85 | SCD (0.44) | SCDALDH1A1KDM4E | |
| SCHEMBL14047421 | 0.84 | SCD (0.59) | SCDHPGDHDAC1ALDH1A1KMT2A | |
| SCHEMBL14047582 | 0.83 | ALDH1A1 (0.41) | SCDALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL14047409 | 0.81 | SCD (0.47) | SCDHDAC1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127349-A2 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | disclosed |