Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047603 | 0.93 | SCD (0.57) | SCDSMN1; SMN2ALDH1A1TSHRKMT2A | |
| SCHEMBL14047625 | 0.90 | SCD (0.57) | SCDSMN1; SMN2ALDH1A1TSHRKMT2A | |
| SCHEMBL14047400 | 0.90 | SCD (0.57) | SCDSMN1; SMN2ALDH1A1TSHRKMT2A | |
| SCHEMBL14047404 | 0.89 | SCD (0.47) | SCDSMN1; SMN2TSHRRAB9ATP53 | |
| SCHEMBL14047409 | 0.89 | SCD (0.47) | SCDSMN1; SMN2TSHRRAB9ATP53 | |
| SCHEMBL14047539 | 0.84 | SCD (0.53) | SCDALDH1A1KMT2AHPGDHDAC1 | |
| SCHEMBL14047595 | 0.82 | SCD (0.56) | SCDALDH1A1HPGDHDAC1 | |
| SCHEMBL14047532 | 0.79 | HDAC1 (0.44) | SCDKMT2AHDAC1P2RX7 | |
| SCHEMBL14047531 | 0.75 | SCD (0.41) | SCDALDH1A1KMT2AHPGD | |
| SCHEMBL14047406 | 0.75 | SCD (0.44) | SCDSMN1; SMN2ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127349-A2 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | disclosed |