Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SCD | O00767 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047605 | 0.84 | SCD (0.47) | KMT2AMEN1SCDSMN1; SMN2CYP2C9 | |
| SCHEMBL14047406 | 0.83 | SCD (0.44) | KMT2AMEN1TSHRSCDSMN1; SMN2 | |
| SCHEMBL240669 | 0.78 | SCD (0.64) | SCDSMN1; SMN2TDP1KDM4E | |
| SCHEMBL14047402 | 0.75 | SCD (0.62) | SCDGAA | |
| SCHEMBL14047625 | 0.70 | SCD (0.57) | KMT2AMEN1TSHRSCDSMN1; SMN2 | |
| SCHEMBL14047400 | 0.70 | SCD (0.57) | KMT2AMEN1TSHRSCDSMN1; SMN2 | |
| SCHEMBL244533 | 0.69 | SCD (0.73) | SCD | |
| SCHEMBL14162281 | 0.69 | SCD (0.45) | TSHRSCDGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL14047409 | 0.67 | SCD (0.47) | TSHRSCDSMN1; SMN2KDM4E | |
| SCHEMBL14047421 | 0.66 | SCD (0.59) | KMT2AMEN1TSHRSCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127349-A2 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | disclosed |