Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 9/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 8/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14047625 | 0.84 | SCD (0.57) | SCDMEN1KMT2AALDH1A1CACNA1I | |
| SCHEMBL14047400 | 0.84 | SCD (0.57) | SCDMEN1KMT2AALDH1A1CACNA1I | |
| SCHEMBL14047577 | 0.83 | KMT2A (0.43) | SCDMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL14047605 | 0.82 | SCD (0.47) | SCDMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL14047539 | 0.78 | SCD (0.53) | SCDKMT2AALDH1A1CACNA1ICACNA1G | |
| SCHEMBL13393741 | 0.78 | SCD (0.49) | SCDALDH1A1TSHR | |
| SCHEMBL243843 | 0.75 | SCD (0.71) | SCD | |
| SCHEMBL14047421 | 0.75 | SCD (0.59) | SCDMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL14047595 | 0.74 | SCD (0.56) | SCDALDH1A1CACNA1ICACNA1GCACNA1H | |
| SCHEMBL14047409 | 0.72 | SCD (0.47) | SCDTSHRTP53LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127349-A2 | HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DISEASES RELATED TO ELEVATED LIPID LEVEL | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | disclosed |