SCHEMBL14047744

SCHEMBL14047744

Cc1ccc(N(c2ccc(-c3ccc(N(c4ccccc4)c4cccc(C)c4)cc3)cc2)c2cccc(C)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 3/20 0.43
HSD17B2 P37059 3/20 0.43
ACHE P22303 2/20 0.41
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41
ALOX12 P18054 1/20 0.41
ALDH1A1 P00352 4/20 0.41
MAPT P10636 3/20 0.41
CYP2C19 P33261 2/20 0.41
KDM4E B2RXH2 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
POLB P06746 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1811899 1.00 HSD17B1 (0.43) HSD17B1HSD17B2ACHELMNATSHR
SCHEMBL19817592 1.00 HSD17B1 (0.43) HSD17B1HSD17B2ACHELMNATSHR
SCHEMBL12926846 1.00 HSD17B1 (0.43) HSD17B1HSD17B2ACHELMNATSHR
SCHEMBL20201647 1.00 HSD17B1 (0.43) HSD17B1HSD17B2ACHELMNATSHR
SCHEMBL14267126 1.00 HSD17B1 (0.43) HSD17B1HSD17B2ACHELMNATSHR
SCHEMBL2774865 1.00 HSD17B1 (0.43) HSD17B1HSD17B2ACHELMNATSHR
SCHEMBL12240207 1.00 HSD17B1 (0.43) HSD17B1HSD17B2ACHELMNATSHR
SCHEMBL14877956 1.00 HSD17B1 (0.43) HSD17B1HSD17B2ACHELMNATSHR
SCHEMBL19649023 1.00 HSD17B1 (0.43) HSD17B1HSD17B2ACHELMNATSHR
SCHEMBL4448698 1.00 HSD17B1 (0.43) HSD17B1HSD17B2ACHELMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10873030-B2 Charge transporting semi-conducting material and electronic device comprising it NOVALED GMBH (DE) 2020-12-22 US disclosed
US-10468601-B2 Charge transporting semi-conducting material and electronic device comprising it NOVALED GMBH (DE) 2019-11-05 US disclosed
US-20190058128-A1 Charge Transporting Semi-Conducting Material and Electronic Device Comprising It NOVALED GMBH (DE) 2019-02-21 US disclosed
US-9755165-B2 Silsesquioxane compound, organic light emitting element, display apparatus, image information processing apparatus, and image forming apparatus CANON KABUSHIKI KAISHA (JP) 2017-09-05 US disclosed
US-20170244033-A1 Charge Transporting Semi-Conducting Material and Electronic Device Comprising It NOVALED GMBH (DE) 2017-08-24 US disclosed
US-20170244033-A1 Charge Transporting Semi-Conducting Material and Electronic Device Comprising It NOVALED GMBH (DE) 2017-08-24 US disclosed
EP-3208863-A1 CHARGE TRANSPORTING SEMI-CONDUCTING MATERIAL AND ELECTRONIC DEVICE COMPRISING IT Novaled GmbH (DE) 2017-08-23 EP disclosed
US-20160118607-A1 SILSESQUIOXANE COMPOUND, ORGANIC LIGHT EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE INFORMATION PROCESSING APPARATUS, AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-04-28 US disclosed
US-9188885-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-11-17 US disclosed
US-9005855-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-04-14 US disclosed
US-8808952-B2 Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-08-19 US disclosed
US-20140079435-A1 NOVEL REACTIVE COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-03-20 US disclosed
US-20140072906-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-03-13 US disclosed
US-8669029-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-11 US disclosed
US-20130052573-A1 NOVEL REACTIVE COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed
EP-1664237-B1 PHOSPHORESCENT POLYMER COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME SHOWA DENKO KK (JP) 2008-10-08 EP disclosed
US-20070155928-A1 Phosphorescent polymer compound and organic light emitting device using the same SHOWDA DENKO K.K. 2007-07-05 US disclosed
US-20070155928-A1 Phosphorescent polymer compound and organic light emitting device using the same SHOWDA DENKO K.K. 2007-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160118607-A1 SILSESQUIOXANE COMPOUND, ORGANIC LIGHT EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE INFORMATION PROCESSING APPARATUS, AND IMAGE FORMING APPARATUS SFXN1, LSS, SLC7A5 HSD17B1 1667/4885HSD17B2 1370/4885ACHE 2810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.