Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 7/20 | 0.38 |
| ▸ | MC3R | P41968 | 7/20 | 0.38 |
| ▸ | MC1R | Q01726 | 7/20 | 0.38 |
| ▸ | GHSR | Q92847 | 2/20 | 0.37 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | PYGM | P11217 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866941 | 0.84 | OPRD1 (0.41) | OPRD1F2MC4RMC3RMC1R | |
| SCHEMBL867816 | 0.84 | GHSR (0.54) | OPRD1F2MC4RMC3RMC1R | |
| SCHEMBL867815 | 0.84 | GHSR (0.54) | OPRD1F2MC4RMC3RMC1R | |
| SCHEMBL866940 | 0.84 | OPRD1 (0.41) | OPRD1F2MC4RMC3RMC1R | |
| SCHEMBL1401582 | 0.80 | F2 (0.48) | OPRD1F2MC4RMC3RMC1R | |
| SCHEMBL867797 | 0.79 | GHSR (0.56) | OPRD1F2GHSRCYP51A1TACR1 | |
| SCHEMBL867796 | 0.79 | GHSR (0.56) | OPRD1F2GHSRCYP51A1TACR1 | |
| SCHEMBL868098 | 0.79 | OPRD1 (0.44) | OPRD1F2GHSRCYP51A1TACR1 | |
| SCHEMBL868099 | 0.79 | OPRD1 (0.44) | OPRD1F2GHSRCYP51A1TACR1 | |
| SCHEMBL10039192 | 0.79 | GHSR (0.54) | OPRD1MC4RMC3RMC1RGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124183-A1 | METHODS OF TREATING OR PREVENTING EMESIS USING GROWTH HORMONE SECRETAGOGUES | HELSINN THERAPEUTICS (U.S.), INC. (US) | 2008-10-16 | — | — | WO | disclosed |