Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 3/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19316250 | 0.94 | KDM4C (0.44) | KDM4CKDM4AEPHX2CNR1DNM1 | |
| SCHEMBL27317414 | 0.88 | KDM4A (0.43) | KDM4CKDM4AEPHX2CNR1DNM1 | |
| SCHEMBL1834258 | 0.88 | PRMT3 (0.41) | KDM4CKDM4AEPHX2CNR1DNM1 | |
| SCHEMBL8746083 | 0.87 | EPHX2 (0.55) | KDM4CKDM4AEPHX2CNR1DNM1 | |
| SCHEMBL1831785 | 0.84 | KDM4A (0.40) | KDM4CKDM4AEPHX2CNR1DNM1 | |
| SCHEMBL8354604 | 0.84 | KDM4C (0.53) | KDM4CKDM4AEPHX2DNM1ALDH1A1 | |
| SCHEMBL10705648 | 0.84 | EPHX2 (0.55) | KDM4CKDM4AEPHX2CNR1DNM1 | |
| SCHEMBL20581810 | 0.83 | EPHX2 (0.47) | KDM4CEPHX2CNR1ALDH1A1NPC1 | |
| SCHEMBL8633444 | 0.82 | CNR1 (0.47) | EPHX2CNR1DNM1ALDH1A1NPC1 | |
| SCHEMBL11161106 | 0.81 | EPHX2 (0.50) | KDM4CKDM4AEPHX2CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1632483-B1 | HETEROCYCLIC SUBSTITUTED CARBONYL DERIVATIVES AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS | AVENTIS PHARMA INC (US) | 2008-10-29 | — | — | EP | disclosed |