SCHEMBL14048792

SCHEMBL14048792

CCC(C)CCCCCCNC

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.50
LMNA P02545 1/20 0.35
KISS1R Q969F8 1/20 0.34
SIGMAR1 Q99720 2/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
ACE2 Q9BYF1 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14548912 1.00 EPHX1 (0.50) EPHX1LMNAKISS1RSIGMAR1HTR2A
SCHEMBL24319959 1.00 EPHX1 (0.50) EPHX1LMNAKISS1RSIGMAR1HTR2A
SCHEMBL13343274 1.00 EPHX1 (0.50) EPHX1LMNAKISS1RSIGMAR1HTR2A
SCHEMBL23784041 0.98 EPHX1 (0.46) EPHX1LMNAKISS1RSIGMAR1HTR2A
SCHEMBL18455001 0.98 EPHX1 (0.46) EPHX1LMNAKISS1RSIGMAR1HTR2A
SCHEMBL12257891 0.98 EPHX1 (0.46) EPHX1LMNAKISS1RSIGMAR1HTR2A
SCHEMBL17900058 0.90
SCHEMBL13213381 0.90
SCHEMBL11651306 0.90
SCHEMBL20094137 0.87 EPHX1 (0.39) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4206325-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE BONAC CORPORATION (JP) 2023-07-05 EP disclosed
US-10675358-B2 Antibody adjuvant conjugates THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2020-06-09 US disclosed
US-20190076547-A1 ANTIBODY ADJUVANT CONJUGATES BOLT BIOTHERAPEUTICS, INC. 2019-03-14 US disclosed
US-20080242626-A1 End-Modified Poly(beta-amino esters) and Uses Thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10675358-B2 Antibody adjuvant conjugates FCGR1A, FCGR3B, FCGR2A EPHX1 422/4885LMNA 4842/4885KISS1R 3589/4885
US-20080242626-A1 End-Modified Poly(beta-amino esters) and Uses Thereof PARN, PARG, POLL EPHX1 4180/4885LMNA 566/4885KISS1R 2381/4885
US-20190076547-A1 ANTIBODY ADJUVANT CONJUGATES FCGR1A, FCGR3B, FCGR2A EPHX1 417/4885LMNA 4851/4885KISS1R 3448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.