Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448276 | 0.80 | TAAR1 (0.50) | TAAR1CTBP2MAPK8MEN1MAPT | |
| SCHEMBL13740254 | 0.80 | CTBP2 (0.47) | TAAR1CTBP2MAPK8MEN1MAPT | |
| SCHEMBL29718576 | 0.78 | CTBP2 (0.55) | TAAR1CTBP2MAPK8MEN1MAPT | |
| SCHEMBL5792021 | 0.78 | TAAR1 (0.48) | TAAR1CTBP2MAPK8MEN1MAPT | |
| SCHEMBL14098647 | 0.78 | PKM (0.59) | TAAR1CTBP2MAPK8MEN1MAPT | |
| SCHEMBL158861 | 0.78 | CTBP2 (0.55) | TAAR1CTBP2MAPK8MEN1MAPT | |
| Hydrochloric Acid SCHEMBL216730 | 0.77 | TAAR1 (0.47) | TAAR1CTBP2MAPK8MEN1MAPT | |
| Hydrochloric Acid SCHEMBL14167478 | 0.77 | CTBP2 (0.53) | TAAR1CTBP2MAPK8MEN1MAPT | |
| SCHEMBL19611620 | 0.75 | LMNA (0.61) | TAAR1CTBP2MAPK8MEN1MAPT | |
| SCHEMBL102788 | 0.75 | LMNA (0.61) | TAAR1CTBP2MAPK8MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985620-A1 | 10a-AZALIDE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2008-10-29 | — | — | EP | disclosed |