Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24619295 | 0.88 | LMNA (0.46) | LMNARXFP1TP53MAPTTHRB | |
| SCHEMBL24619399 | 0.87 | LMNA (0.58) | LMNARXFP1TP53MAPTTHRB | |
| SCHEMBL30086073 | 0.87 | LMNA (0.58) | LMNARXFP1TP53MAPTTHRB | |
| SCHEMBL10000316 | 0.83 | LMNA (0.59) | LMNARXFP1TP53MAPTTHRB | |
| SCHEMBL29925102 | 0.82 | LMNA (0.57) | LMNARXFP1TP53MAPTTHRB | |
| SCHEMBL24619206 | 0.81 | LMNA (0.55) | LMNARXFP1TP53MAPTTHRB | |
| SCHEMBL24619230 | 0.81 | MAPT (0.52) | LMNARXFP1TP53MAPTTHRB | |
| SCHEMBL14048802 | 0.80 | LMNA (0.55) | LMNARXFP1TP53MAPTTHRB | |
| SCHEMBL13054386 | 0.80 | LMNA (0.55) | LMNARXFP1TP53MAPTTHRB | |
| SCHEMBL24105990 | 0.80 | LMNA (0.68) | LMNARXFP1TP53MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |