Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13746209 | 0.89 | HTR6 (0.40) | HTR6PTPN11SCDSCN9ABRD4 | |
| SCHEMBL8192188 | 0.81 | PDPK1 (0.47) | HTR6PTPN11BRD4PDPK1 | |
| SCHEMBL16697223 | 0.81 | HTR6 (0.46) | HTR6SCDSCN9AROCK2PDPK1 | |
| SCHEMBL3506204 | 0.80 | BRD4 (0.40) | HTR6PTPN11SCDSCN9ABRD4 | |
| SCHEMBL16697663 | 0.79 | HTR6 (0.47) | HTR6SCDSCN9APDPK1PIK3C3 | |
| SCHEMBL16697816 | 0.79 | HTR6 (0.46) | HTR6SCDSCN9APDPK1 | |
| SCHEMBL3507232 | 0.78 | CYP2C19 (0.43) | HTR6SCDSCN9AROCK2PIK3CA | |
| SCHEMBL8488593 | 0.78 | HTR6 (0.38) | HTR6PTPN11BRD4PDPK1DRD2 | |
| SCHEMBL3505606 | 0.76 | BRD4 (0.39) | HTR6PTPN11SCDSCN9ABRD4 | |
| SCHEMBL25924807 | 0.74 | TNK2 (0.46) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432375-B2 | JNK inhibitors | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2008-10-07 | — | — | US | disclosed |