Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | CA9 | Q16790 | 7/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.42 |
| ▸ | MAG | P20916 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14031247 | 1.00 | LMNA (0.56) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL4782512 | 0.87 | CYP2D6 (0.55) | ALDH1A1CYP3A4MAPTTHRBCYP2D6 | |
| SCHEMBL4782498 | 0.87 | CYP2D6 (0.55) | ALDH1A1CYP3A4MAPTTHRBCYP2D6 | |
| SCHEMBL18710677 | 0.85 | LMNA (0.60) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL16882358 | 0.85 | LMNA (0.60) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL24219925 | 0.85 | LMNA (0.60) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL15344529 | 0.85 | LMNA (0.60) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL23046595 | 0.85 | LMNA (0.60) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL19767509 | 0.85 | LMNA (0.60) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL15333945 | 0.85 | LMNA (0.60) | LMNAKMT2AALDH1A1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080241903-A1 | In vivo site-sepecific incorporation of N-acetyl-galactosamine amino acids in eubacteria | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-10-02 | — | — | US | disclosed |