Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 14/20 | 0.63 |
| ▸ | NOS3 | P29474 | 13/20 | 0.63 |
| ▸ | NOS2 | P35228 | 6/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105156 | 0.91 | NOS1 (0.55) | NOS1NOS3NOS2KCNH2TP53 | |
| SCHEMBL2676245 | 0.90 | NOS1 (0.63) | NOS1NOS3NOS2KCNH2TP53 | |
| SCHEMBL4113853 | 0.88 | NOS3 (0.62) | NOS1NOS3NOS2KCNH2TP53 | |
| Hydrochloric Acid SCHEMBL2675930 | 0.87 | NOS3 (0.64) | NOS1NOS3NOS2KCNH2TP53 | |
| SCHEMBL2675705 | 0.86 | NOS3 (0.63) | NOS1NOS3NOS2KCNH2TP53 | |
| SCHEMBL2675060 | 0.85 | NOS3 (0.62) | NOS1NOS3NOS2KCNH2TP53 | |
| SCHEMBL4107660 | 0.85 | NOS3 (0.57) | NOS1NOS3NOS2KCNH2TP53 | |
| SCHEMBL2676597 | 0.85 | NOS3 (0.63) | NOS1NOS3NOS2KCNH2TP53 | |
| SCHEMBL2675640 | 0.85 | NOS3 (0.63) | NOS1NOS3NOS2KCNH2TP53 | |
| Hydrochloric Acid SCHEMBL2675580 | 0.84 | NOS3 (0.59) | NOS1NOS3NOS2KCNH2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116308-A1 | QUINOLONE AND TETRAHYDROQUINOLINE AND RELATED COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON, INC. (CA) | 2008-10-02 | — | — | WO | disclosed |