Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 11/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14049844 | 0.91 | TRPV1 (0.46) | TRPV1NR1H4RORCPTPN1 | |
| SCHEMBL14049680 | 0.90 | TRPV1 (0.46) | TRPV1NR1H4RORCPTPN1 | |
| SCHEMBL14049773 | 0.90 | TRPV1 (0.43) | TRPV1NR1H4RORCPTPN1 | |
| SCHEMBL14049682 | 0.89 | TRPV1 (0.43) | TRPV1NR1H4RORCPTPN1 | |
| SCHEMBL14049884 | 0.89 | RORC (0.45) | TRPV1NR1H4RORCPTPN1 | |
| SCHEMBL14049672 | 0.86 | TRPV1 (0.41) | TRPV1NR1H4RORCPTPN1 | |
| SCHEMBL13637574 | 0.86 | RORC (0.47) | TRPV1NR1H4RORCPTPN1GPBAR1 | |
| SCHEMBL13637654 | 0.85 | RORC (0.42) | TRPV1NR1H4RORCPTPN1 | |
| SCHEMBL13637776 | 0.84 | TRPV1 (0.42) | TRPV1NR1H4RORC | |
| SCHEMBL13637674 | 0.83 | RORC (0.48) | TRPV1NR1H4RORCGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127364-A2 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |