SCHEMBL13637776

SCHEMBL13637776

COC(=O)c1ccc(CNC(=O)c2cccc(CCNC(=O)C34CCCC3C3CCC5C6(C)CCC(O)C(C)(C)C6CCC5(C)[C@]3(C)CC4)c2)nc1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 1/20 0.42
▸ RORC P51449 13/20 0.41
▸ NR1H4 Q96RI1 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13637654 0.94 RORC (0.42) TRPV1RORCNR1H4
SCHEMBL13628307 0.89 GPBAR1 (0.49) TRPV1RORC
SCHEMBL14049860 0.88 ROCK2 (0.35) TRPV1RORCNR1H4
SCHEMBL13637464 0.87 TRPV1 (0.48) TRPV1RORC
SCHEMBL13637653 0.86 TRPV1 (0.38) TRPV1RORC
SCHEMBL14049844 0.86 TRPV1 (0.46) TRPV1RORCNR1H4
SCHEMBL13628305 0.86 RORC (0.45) TRPV1RORCNR1H4
SCHEMBL14049680 0.85 TRPV1 (0.46) TRPV1RORCNR1H4
SCHEMBL14049884 0.84 RORC (0.45) TRPV1RORCNR1H4
SCHEMBL14049772 0.84 TRPV1 (0.42) TRPV1RORCNR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275583-A1 ANTIVIRAL COMPOUNDS AND USE THEREOF MYRIAD GENETICS, INCORPORATED (US) 2009-11-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275583-A1 ANTIVIRAL COMPOUNDS AND USE THEREOF MAVS, ZC3HAV1, EIF2AK2 TRPV1 3411/4885RORC 514/4885NR1H4 1225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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