Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 5/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14049874 | 0.92 | ABCB1 (0.37) | ABCB1NR1H4PTPN1HSD17B10TDP1 | |
| SCHEMBL4445240 | 0.89 | TRPV1 (0.50) | ABCB1NR1H4PTPN1TRPV1RORC | |
| SCHEMBL14049921 | 0.88 | HSD17B10 (0.55) | HSD17B10TDP1TRPV1RORC | |
| SCHEMBL14049877 | 0.87 | PTPN1 (0.41) | NR1H4PTPN1HSD17B10TDP1TRPV1 | |
| SCHEMBL4453958 | 0.81 | RORC (0.47) | ABCB1NR1H4TRPV1RORC | |
| SCHEMBL14049776 | 0.78 | HSD17B10 (0.56) | PTPN1HSD17B10TDP1TRPV1RORC | |
| SCHEMBL4445877 | 0.78 | TRPV1 (0.66) | PTPN1TRPV1RORC | |
| SCHEMBL14049880 | 0.78 | HSD17B10 (0.42) | HSD17B10TDP1TRPV1RORC | |
| SCHEMBL13637465 | 0.78 | TRPV1 (0.66) | PTPN1TRPV1RORC | |
| SCHEMBL13628320 | 0.78 | TRPV1 (0.66) | PTPN1TRPV1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127364-A2 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |