Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28742442 | 1.00 | — | — | |
| Bromide SCHEMBL9423803 | 1.00 | — | — | |
| Bromide SCHEMBL4945105 | 1.00 | — | — | |
| Bromide SCHEMBL16237278 | 1.00 | — | — | |
| Bromide SCHEMBL21596248 | 1.00 | — | — | |
| Bromide SCHEMBL27827328 | 1.00 | — | — | |
| Bromide SCHEMBL6685399 | 1.00 | — | — | |
| Bromide SCHEMBL3844728 | 1.00 | — | — | |
| Bromide SCHEMBL5775102 | 0.82 | — | — | |
| Bromide SCHEMBL3326847 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 561 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4211119-B1 | 2-AMINOQUINAZOLINES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2026-05-13 | — | — | EP | claimed |
| US-12570640-B2 | 2-aminoquinazolines as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof | MERCK SHARP & DOHME LLC (US) | 2026-03-10 | — | — | US | claimed |
| CN-113174032-B | Fluoro condensed ring benzothiadiazole polymer acceptor material and preparation method thereof | 香港科技大学深圳研究院 | 2023-11-07 | — | — | CN | claimed |
| US-20230303540-A1 | 2-AMINOQUINAZOLINES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2023-09-28 | — | — | US | claimed |
| EP-4211119-A1 | 2-AMINOQUINAZOLINES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Merck Sharp & Dohme LLC (US) | 2023-07-19 | — | — | EP | claimed |
| CN-115216051-A | Easy-to-demould and easy-to-form foaming polypropylene bead | 无锡会通轻质材料股份有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-217554594-U | Steel-lined fluorine-bromine-water comprehensive separation bottle for extracting bromine from seawater | 金盛海洋科技有限公司 | 2022-10-11 | — | — | CN | claimed |
| WO-2022179307-A1 | METHOD FOR PREPARING MULTIFUNCTIONAL INTESTINAL DIAGNOSIS AND TREATMENT FORMULATION, AND PRODUCT THEREOF | 上海纳米技术及应用国家工程研究中心有限公司 | 2022-09-01 | — | — | WO | claimed |
| CN-109336883-B | Bicyclic heterocyclic compounds and their therapeutic use | 阿斯特克斯治疗有限公司 | 2022-06-14 | — | — | CN | claimed |
| WO-2022051337-A1 | 2-AMINOQUINAZOLINES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME CORP. (US) | 2022-03-10 | — | — | WO | claimed |
| CN-1094722-A | Novel treatment | SMITHKLINE BEECHAM PLC (US) | 1994-11-09 | — | — | CN | claimed |
| EP-0594225-A1 | Process for preparing polyalkyl tetrahydronaphtalenes | Union Camp Corporation (US) | 1994-04-27 | — | — | EP | claimed |
| US-5298483-A | Biodegradable | TROPICANA PRODUCTS, INC. (US) | 1994-03-29 | — | — | US | claimed |
| WO-1993019597-A1 | PLANT BIOREGULATORY COMPOSITION AND METHOD USING (BENZYL SUBSTITUTED) TRIALKYLAMINE ETHER COMPOUNDS | TROPICANA PRODUCTS, INC. (US) | 1993-10-14 | — | — | WO | claimed |
| EP-0210647-B1 | PYRIDAZINONE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND INSECTICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-10-28 | — | — | EP | claimed |
| US-4997473-A | Certain 2-(2'-substituted benzoyl)-4-proparoyl-1,3-cyclohexanedione herbicides | ICI AMERICAS INC. (US) | 1991-03-05 | — | — | US | claimed |
| EP-0315025-A1 | Amide-imide copolymers and process for the preparation thereof | GENERAL ELECTRIC COMPANY (US) | 1989-05-10 | — | — | EP | claimed |
| EP-0113108-A2 | Benzamidine group compounds and agricultural fungicidal compositions containing the same | UBE INDUSTRIES, LTD. (JP) | 1984-07-11 | — | — | EP | claimed |
| US-4054458-A | SUBSTITUTED AMINO-TRIAZINES | FUJI PHOTO FILM CO., LTD. (JA) | 1977-10-18 | — | — | US | claimed |
| US-3937824-A | COMPOSITIONS AND METHODS OF KILLING INSECTS AND ACARIDS USING ALKOXYIMINO CARBAMOYLOXY PHOSPHORUS COMPOUNDS | VELSICOL CHEMICAL CORPORATION (US) | 1976-02-10 | — | — | US | claimed |