Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL140501 | 0.82 | — | — | |
| Bromide SCHEMBL82194 | 0.82 | — | — | |
| Bromide SCHEMBL6685399 | 0.82 | — | — | |
| Bromide SCHEMBL312889 | 0.82 | — | — | |
| Bromide SCHEMBL21596248 | 0.82 | — | — | |
| Bromide SCHEMBL11224381 | 0.82 | — | — | |
| Bromide SCHEMBL5154869 | 0.82 | — | — | |
| Fluoride SCHEMBL37280 | 0.82 | — | — | |
| Fluoride SCHEMBL82520 | 0.82 | — | — | |
| Fluoride SCHEMBL2779223 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137643-A1 | METHOD FOR SYNTHESIZING CYCLOHEXYL-SUBSTITUTED PHOSPHINES | BASF SE (DE) | 2010-06-03 | — | — | US | disclosed |
| US-RE30430-E | Catalyst treatment | DENKA CHEMICAL CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4081460-A | IN SITU REGENERATION AND STABILIZATION OF CATALYST WITH A PHOSPHORUS COMPOUND | DENKA CHEMICAL CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-4006168-A | Catalyst treatment | PETRO-TEX CHEMICAL CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |