Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259634 | 0.86 | MAPT (0.37) | MAPTL3MBTL1LMNA | |
| SCHEMBL258728 | 0.70 | MAPT (0.35) | MAPTL3MBTL1LMNA | |
| SCHEMBL258715 | 0.70 | MAPT (0.35) | MAPTL3MBTL1LMNA | |
| SCHEMBL259633 | 0.69 | POLB (0.33) | MAPT | |
| SCHEMBL13810676 | 0.64 | CA1 (0.34) | — | |
| SCHEMBL16488059 | 0.63 | ACHE (0.44) | MAPTL3MBTL1LMNA | |
| SCHEMBL2693261 | 0.62 | CYP1A2 (0.36) | MAPTL3MBTL1LMNA | |
| SCHEMBL10961316 | 0.62 | ACHE (0.44) | MAPTL3MBTL1LMNA | |
| SCHEMBL20906761 | 0.62 | KDM4E (0.31) | — | |
| Water SCHEMBL27748223 | 0.61 | MEN1 (0.38) | L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117054-A2 | CHIRAL DIPHOSPHINES, METHODS FOR THEIR PREPARATION, TRANSITION METAL COMPLEXES COMPRISING THEM AND USE IN CHIRAL SYNTHESIS | CELTIC CATALYSTS LIMITED (IE) | 2008-10-02 | — | — | WO | disclosed |