Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16487758 | 0.92 | ACHE (0.39) | ACHEPTPN1NR3C1NR3C2RAPGEF4 | |
| SCHEMBL25240456 | 0.83 | ACHE (0.41) | ACHEPTPN1MAPTL3MBTL1NR3C1 | |
| SCHEMBL129762 | 0.80 | ACHE (0.57) | ACHEPTPN1MAPTL3MBTL1NR3C1 | |
| SCHEMBL258715 | 0.73 | MAPT (0.35) | ACHEMAPTL3MBTL1RAPGEF4ALDH1A1 | |
| SCHEMBL258728 | 0.73 | MAPT (0.35) | ACHEMAPTL3MBTL1RAPGEF4ALDH1A1 | |
| SCHEMBL13083360 | 0.71 | ACHE (0.48) | ACHEPTPN1MAPTL3MBTL1NR3C1 | |
| SCHEMBL10196604 | 0.71 | ACHE (0.76) | ACHEPTPN1MAPTL3MBTL1LMNA | |
| SCHEMBL11460644 | 0.70 | RAPGEF4 (0.38) | ACHEMAPTRAPGEF4ALDH1A1LMNA | |
| SCHEMBL542689 | 0.70 | ACHE (0.46) | ACHEPTPN1MAPTL3MBTL1NR3C1 | |
| SCHEMBL17662618 | 0.70 | ACHE (0.46) | ACHEPTPN1MAPTL3MBTL1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957181-B2 | Preparation process for cyclic conjugated polymer and polymerization catalyst for cyclic conjugated polymer | SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) | 2015-02-17 | — | — | US | disclosed |