Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | GMNN | O75496 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27503997 | 1.00 | GPR84 (0.55) | GPR84DNM1TLR2MAPK1GMNN | |
| SCHEMBL2356631 | 1.00 | GPR84 (0.55) | GPR84DNM1TLR2MAPK1GMNN | |
| SCHEMBL2356636 | 1.00 | GPR84 (0.55) | GPR84DNM1TLR2MAPK1GMNN | |
| SCHEMBL147666 | 1.00 | GPR84 (0.55) | GPR84DNM1TLR2MAPK1GMNN | |
| SCHEMBL9406666 | 1.00 | GPR84 (0.55) | GPR84DNM1TLR2MAPK1GMNN | |
| SCHEMBL147665 | 1.00 | GPR84 (0.55) | GPR84DNM1TLR2MAPK1GMNN | |
| SCHEMBL2315839 | 1.00 | GPR84 (0.55) | GPR84DNM1TLR2MAPK1GMNN | |
| SCHEMBL113225 | 1.00 | GPR84 (0.55) | GPR84DNM1TLR2MAPK1GMNN | |
| SCHEMBL2678427 | 1.00 | GPR84 (0.55) | GPR84DNM1TLR2MAPK1GMNN | |
| SCHEMBL27504689 | 1.00 | GPR84 (0.55) | GPR84DNM1TLR2MAPK1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940028-B1 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE | CORIXA CORP (US) | 2017-08-16 | — | — | EP | disclosed |
| EP-2940028-A1 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE | CORIXA CORPORATION (US) | 2015-11-04 | — | — | EP | disclosed |
| EP-2940027-A1 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE | CORIXA CORPORATION (US) | 2015-11-04 | — | — | EP | disclosed |
| EP-1589934-B1 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE | CORIXA CORP (US) | 2015-09-23 | — | — | EP | disclosed |
| EP-1776375-B1 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE | CORIXA CORP (US) | 2015-04-01 | — | — | EP | disclosed |
| US-20120058148-A1 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE | CORIXA CORPORATION (US) | 2012-03-08 | — | — | US | disclosed |
| US-7960522-B2 | Certain aminoalkyl glucosaminide phosphate compounds and their use | CORIXA CORPORATION (US) | 2011-06-14 | — | — | US | disclosed |
| CN-101863930-A | Certain aminoalkyl glucosaminide phosphate compounds and their purposes | CORIXA CORP | 2010-10-20 | — | — | CN | disclosed |
| CN-101080234-A | Certain aminoalkyl glucosaminide phosphate compounds and their use | CORIXA CORP (US) | 2007-11-28 | — | — | CN | disclosed |
| CN-101010328-A | Certain aminoalkyl glucosaminide phosphate compounds and their use | CORIXA CORP (US) | 2007-08-01 | — | — | CN | disclosed |
| EP-1776375-A2 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE | CORIXA CORPORATION (US) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006016997-A2 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE | CORIXA CORPORATION (US) | 2006-02-16 | — | — | WO | disclosed |
| EP-1589934-A2 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE | CORIXA CORPORATION (US) | 2005-11-02 | — | — | EP | disclosed |
| US-20050227943-A1 | Certain aminoalkyl glucosaminide phosphate compounds and their use | CORIXA CORPORATION (US) | 2005-10-13 | — | — | US | disclosed |
| WO-2004062599-A2 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE | CORIXA CORPORATION (US) | 2004-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058148-A1 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE | IFNG, CD68, IL2 | GPR84 672/4885DNM1 4561/4885TLR2 42/4885 |
| US-20050227943-A1 | Certain aminoalkyl glucosaminide phosphate compounds and their use | IFNG, CD68, IL2 | GPR84 672/4885DNM1 4561/4885TLR2 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.